I highly recommend Cooper ST Maxx's! I have a set of LT255/80R17 with about 10K on them. I run them on a GX470 that weighs in at about 5k lbs loaded for a weekend.
On the highway, they are quiet, ride well, they balanced easily and track really well. They have better then stock wet traction and they are also wearing very well. I'm fully expecting to get at least 50k out of them of mixed highway/trail use.
On the trail they have been even better. I was a bit concerned that the side walls of the E rated tires wouldn't flex as would like given my moderate weight. After having them they are perfect. They flatten out just enough at about 25 psi to be great running dirt/fire roads and really take out the bumps without heating up. They've been through lots of miles of sharp/jagged rock without any issues (White Rim, Big Bend and various other NV/Utah trails). The big lugs grip really well and do a decent job not picking up rocks. I ran a really sandy trail in Utah (Barracks Road) and they were exceptional in the deep/lose sand.
My last pitch is to at consider a tall skinny tire for your overland rig. I did a lot of reading on the pros and cons and decided to pull the trigger (just search tall/skinny tires and all the forums have tons of info for and against). I went from a stock tire (29"x10.5") to what is essentially a 33"x10" vs the more common 33"x12.5". I picked up several inches of ground clearance, I don't rub anywhere with a 2.5-3" lift (no spacers) AND gained a full 1 MPG (went from averaging 15.5 MPG with stock height and tires to 16.5 MPG with lift and 33"s. Apparently 33"s are a more economical fit with the stock gearing (3.73). Needless to say I was pleasantly surprised. I was expecting to lose 2-3 MPG and instead I gained! In the overlanding world, range is a big factor and at least with this specific vehicle/tire setup I added nearly 75 miles of range when compared to going with other's MPG experiences going with 33x12.5s. May not be the best fit for everyone, but definitely worth considering depending on your vehicle and your driving style.